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Postion:Product Catalog >MRT68921 dihydrochloride
MRT68921 dihydrochloride
  • MRT68921 dihydrochloride

MRT68921 dihydrochloride NEW

Price $35 $56 $94
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: MRT68921 dihydrochloride CAS No.: 2080306-21-2
Purity: 98.91% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameMRT68921 dihydrochloride
DescriptionMRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).
In vitroMRT68921 inhibits ULK1 and ULK2 in vitro and block autophagy in cells.?MRT68921 is the most potent inhibitor of both ULK1 and ULK2, with greater than a 15-fold reduction in the IC50 for ULK1 (2.9 nm) and greater than a 30-fold reduction for ULK2 (1.1 nm).?Autophagy-inhibiting capacity of the compounds is specifically through ULK1.?ULK1 inhibition results in accumulation of stalled early autophagosomal structures, indicating a role for ULK1 in the maturation of autophagosomes as well as initiation[1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : 33.33 mg/mL (65.67 mM), Sonication is recommended.
DMSO : 2 mg/mL (3.94 mM), Sonication is recommended.
Keywordsinhibit | MRT-68921 | ULK | MRT-68921 dihydrochloride | MRT68921 | Inhibitor | MRT 68921 | Unc-51 like kinase | MRT68921 dihydrochloride | MRT 68921 Dihydrochloride | MRT-68921 Dihydrochloride | MRT68921 Dihydrochloride
Inhibitors RelatedStavudine | Xylitol | Myricetin | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Oxyresveratrol | Paeonol | Naringin | Gefitinib
Related Compound LibrariesBioactive Compound Library | Kinase Inhibitor Library | Autophagy Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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