Mometasone furoate (MF) is a new fluorine-free glucocorticoid derivative with high efficacy and less adverse reactions. Mometasone furoate is a fluorine-free hormone with the chemical name 9,21-dichloro-11b, 17-dihydroxy-16a-methyl pregnane-1,4-dichemicalbook en-3,20-dione 17-(2-furoate) . The C1,2 double bond of the molecular structure has the function of increasing therapeutic effect, the chlorination of the C9,21 position enhances the anti-inflammatory activity, the C16 position methyl reduces the salt metabolism, and the C17 position furoate fat increases the lipophilicity, and enhances the local therapeutic effect, reduce systemic absorption and reduce the risk of adverse reactions.