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Postion:Product Catalog >MK2-IN-1 hydrochloride
MK2-IN-1 hydrochloride
  • MK2-IN-1 hydrochloride

MK2-IN-1 hydrochloride NEW

Price $31 $53 $109
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: MK2-IN-1 hydrochloride CAS No.: 1314118-94-9
Purity: 99.67% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameMK2-IN-1 hydrochloride
DescriptionMK2-IN-1 hydrochloride (MK 25) is a highly selective, non-ATP competitive inhibitor of p38/mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2 or MK2, IC50: 0.11 μM) [1].
In vitroMK2-IN-1 has been shown to inhibit pro-inflammatory cytokine secretion from the human THP-1 acute monocytic leukemia cell line, causing inhibition of LPS-stimulated TNF-α (IC50: 4.4 μM) and IL-6 (IC50: 5.2 μM) secretion.1 It can also inhibit IL-1β-stimulated matrix-metalloprotease 13 secretion from the SW1353 chondrosarcoma cell line (IC50: 5.7 μM) and human primary chondrocyte cultures (IC50: 2.2 μM) [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (98.15 mM)
H2O : Insoluble
KeywordsMK2-IN-1 Hydrochloride | inhibit | MK25 | MAP kinase activated protein kinase 2 | MAPK activated protein kinase 2 | MAPKAPK2 (MK2) | Inhibitor | MK2IN1 hydrochloride | MK2 IN 1 hydrochloride | MAPKAP kinase 2 | MK-25 | MK-2-IN-1 hydrochloride | Mitogen-activated protein kinase activated protein kinase 2
Inhibitors RelatedSodium lauryl sulfoacetate | Nomilin | Vemurafenib | CMPD1 | SKLB-163 | MBM-55S | sodium lauroyl-α-hydroxyethyl sulfonate | NQDI-1 | Takinib | NG25 | MK2-IN-3 hydrate | Selonsertib
Related Compound LibrariesOsteogenesis Compound Library | Anti-Colorectal Cancer Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Inhibitor Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | Anti-Liver Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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