Mirogabalin
Price | Get Latest Price | ||
Package | 5kg | 25kg | 50kg |
Min. Order: | 1kg |
Supply Ability: | 1000 |
Update Time: | 2024-12-25 |
Product Details
Product Name: Mirogabalin | CAS No.: 1138245-13-2 |
Min. Order: 1kg | Purity: 98 |
Supply Ability: 1000 | Release date: 2024/12/25 |
Product Name: Mirogabalin
Synonyms: 2-((1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl)acetic acid;Mirogabalin;Asapiprant;[(1R,5S,6S)-6-(Aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid;A200-0700;DS5565;DS5565;A200-0700;2-[(1R,5S,6S)-6-(aminomethyl)-3-ethyl-6-bicyclo[3.2.0]hept-3-enyl]acetic acid
CAS: 1138245-13-2
MF: C12H19NO2
MW: 209.28
Mirogabalin is a calcium channel blocker with analgesic effects. It binds to the α2δ-1 and α2δ-2 subunits of voltage-dependent Ca2+ channels. Mirogabalin has potent and sustained analgesic effects (ED50 = 2.5 mg/kg) in rats with diabetes induced by streptozotocin (STZ; ). Mirogabalin does not inhibit activities associated with CNS adverse effects of analgesics, such as rotarod performance (ID50 = 9.4 mg/kg) or locomotor activity (ID50 = 43.9 mg/kg), at its effective dose. Formulations containing mirogabalin are in clinical trials for diabetic peripheral neuropathic pain.
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- Since: 2024-03-12
- Address: Room 02-31, 13 / F, Building 9, Guannan Fuxing Medical Park Phase II, No.58, Guanggu Avenue, East La