Methyllycaconitine citrate NEW
Price | $149 |
Package | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Methyllycaconitine citrate | CAS No.: 351344-10-0 |
Purity: 98.69% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Methyllycaconitine citrate |
Description | Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier. |
In vitro | Pretreatment with 5 and 10 μM Methyllycaconitine citrate inhibited the decreased cell viability induced by Aβ25–35, which suggested that Methyllycaconitine citrate had a protective effect against Aβ-induced cytotoxicity. Furthermore, cell viability did not decrease after exposure to Methyllycaconitine citrate (2.5, 5, 10, 20 uM), which suggests a good safety profile[1]. |
In vivo | The effect of MLA on acute METH-induced effects and neurotoxicity in mice was tested using an in vivo model. The results indicate that MLA (6 mg/kg) inhibited 50% of the METH-induced climbing behavior[2]. |
Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 100 mg/mL (114.30 mM), Sonication is recommended. H2O : 1 mg/mL (1.14 mM), Sonication is recommended. |
Inhibitors Related | Adiphenine hydrochloride | Nanofin | Arecoline hydrobromide | Forskolin | CLOZAPINE N-OXIDE | Pilocarpine nitrate | Ribavirin | Adenine | Choline chloride | Propoxur |
Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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