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Postion:Product Catalog >API>Antineoplastic agents>Antimetabolites, Antineoplastic>Methotrexate
Methotrexate
  • Methotrexate
  • Methotrexate
  • Methotrexate
  • Methotrexate
  • Methotrexate

Methotrexate

Price $15
Package 1kg
Min. Order: 10kg
Supply Ability: 20tons
Update Time: 2023-07-31

Product Details

Product Name: Methotrexate CAS No.: 59-05-2
Min. Order: 10kg Purity: 99%
Supply Ability: 20tons Release date: 2023/07/31

Basic Info.

Grade
Pharmaceutcial Grade
CAS
59-05-2
Storage
Cool Dry Place
Deliver Time
5-10 Days
Appearance
Yellow Powder
Test Method
HPLC UV
Sample
Available
Shipping Method
Air(UPS, FedEx, TNT, EMS) or Sea
Mf
C20h22n8o5
Einecs No.
200-413-8
MW
454.44
Refractive Index
1.6910 (Estimate)
Density
1.4080 (Rough Estimate)
Transport Package
Bag or Drum
Specification
1kg/bag 25kg/drum
Origin
China
Production Capacity
10000kg/Months

Product Description

Product Description
NameMethotrexate
Synonyms(+)-Amethopterin; (+)-4-Amino-10-methylfolic acid; N-(p-(((2,4-Diamino-6-pteridinyl)methyl)methylamino)benzoyl)-L-glutamic acid
Molecular FormulaC20H22N8O5
Molecular Weight454.44
CAS Registry Number59-05-2
EINECS200-413-8
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate arrests the cell cycle in late G1/S-phase, therefore inhibiting the synthesis of DNA, RNA, thymidylates, and proteins. In the previous cases the inhibition of enzymes involved in purine metabolism, leading to accumulation of adenosine, or the suppression of intercellular adhesion molecule expression by T cells as the main mechanism of action by methotrexate. The compound has been observed to irreversibly inhibit dihydrofolate reductase (DHFR) and thymidylate synthetase (TS). Methotrexate has been shown to modulate inflammation by promoting adenosine release or inhibiting transmethylation reactions. In adherent splenic cells, IL-1 production was decreased by methorexate.

Packaging & ShippingArticle illustration

Company Profile Introduction

Hebei Linwo New Material Technology Co., LTD is located in Xingtai, Hebei, Hongxing Street, Xiangdu District.We are a manufacturer and trader in China, with 10 years of experience in the export of chemical and pharmaceutical raw materials .? We are all promoted on chemicalbook platform.? More than ten years of export experience Specializing in the production of pharmaceutical raw materials, odybuilding products, sexual enhancement products, local anesthesia products, best-selling pharmaceutical intermediates, etc.? The quality of our products has reached the international leading level.? Can provide free samples to provide testing.? Provide product customization services.? We have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia.? Overseas warehouses can provide some of the best-selling products.? We look forward to the cooperation of local powerful distributors and factories.? Deliver the package as soon as possible.? We guarantee that 100% of the packages you order pass the customs of the United States, Mexico, Canada, the 27 EU countries, the United Kingdom, Australia, and Southeast Asian countries.? We have a strong customs clearance agency in these countries, and our customs clearance company will clear your parcel without any customs issues, sometimes even 1000 kg.? In order to ensure 100% receipt of your package, if there is any customs issue, we promise to reissue it again free of charge.? Let you experience our strong transportation and customs clearance capabilities.

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  • Address: Room 601, Unit 1, Building 1, 188 Xinhuali, North Xinhua Road, Xiangdu District, Xingtai city, Hebei
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