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Postion:Product Catalog >Analytical Chemistry>Standard>Pharmaceutical Impurity Reference Standards>Methotrexate metabolite
Methotrexate metabolite
  • Methotrexate metabolite

Methotrexate metabolite NEW

Price $48 $77 $116
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Methotrexate metabolite CAS No.: 19741-14-1
Purity: 99.7% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameMethotrexate metabolite
DescriptionMethotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant.
In vitroMethotrexate metabolite was the most active, with 50% inhibitory concentrations in vitro of 446 ng/ml against the antifolate-sensitive strain and 812 ng/ml against the highly resistant strain under physiological folate conditions. Methotrexate metabolite potentiates the activity of the sulfone dapsone, an inhibitor of dihydropteroate synthase, but not that of chlorcycloguanil, a known inhibitor of dihydrofolate reductase (DHFR)[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 4 mg/mL (12.30 mM)
KeywordsInhibitor | Antifolate | Drug Metabolite | inhibit | Methotrexate metabolite
Inhibitors RelatedPemetrexed | Methotrexate | Clofibric acid | Mycophenolate Mofetil | CLOZAPINE N-OXIDE | Monomethyl fumarate | Trimethoprim | Isonicotinic acid | Ampyrone | Nicotinamide N-oxide
Related Compound LibrariesAnti-Parasitic Compound Library | Bioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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