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Postion:Product Catalog >MeTC7
MeTC7
  • MeTC7

MeTC7 NEW

Price $46 $139 $258
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: MeTC7 CAS No.: 1817841-22-7
Supply Ability: 10g Release date: 2024/11/15

Product Introduction

Bioactivity

名稱MeTC7
描述MeTC7 is a vitamin D receptor (VDR) antagonist with antitumor activity that inhibits PD-L1 and may inhibit the growth of xenografts and transgenic tumors in vivo.
體外活性MeTC7 disrupts the VDR-Ligand-binding domain in Silico. MeTC7 shows potent VDR inhibition activity with an IC50=2.9 μM. [1] Treatment with 250 nM MeTC7 for 18 h was able to inhibit the expression of RXRα and Importin-4 and induce PARP1 cleavage, thereby inhibiting the viability of ovarian cancer cells. [1]
體內(nèi)活性By intraperitoneal injection of 10 mg/kg MeTC7 was able to inhibit the growth of spontaneous transgenic TH-MYCN neuroblastoma and xenograft tumors in vivo. [1]
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 10 mg/mL(16.16 mM), Sonication is recommended.
關(guān)鍵字Miransertib dimesylate | MeTC7 | Miransertib mesylate
相關(guān)產(chǎn)品Acenocoumarol | Ercalcidiol | Retinyl acetate | DL-Panthenol | Maxacalcitol | Calcipotriol | Ercalcitriol | 5,6-trans-Vitamin D3 | Biotin | Calcipotriol monohydrate | Coumetarol | 24, 25-Dihydroxy VD2

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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