Medetomidine NEW
| Price | $32 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-12 |
Product Details
| Product Name: Medetomidine | CAS No.: 86347-14-0 |
| Purity: 99.88% | Supply Ability: 10g |
| Release date: 2025/06/12 |
Product Introduction
Bioactivity
| Name | Medetomidine |
| Description | Medetomidine (MPV785 free base) is a selective and orally available α2-adrenoceptor agonist, Ki=1.08 nM, with sedative and analgesic effects and vasoconstrictive hypoxic side effects, and is commonly used in small animal anesthesia. |
| In vitro | Both enantiomers of Medetomidine (dex- and levoMedetomidine) inhibit cytochrome P450-dependent drug-metabolizing activity in rat and human liver microsomes(100 μg/kg ;from 17 to 23 min.; both enantiomers)[1]. In Rainbow trout(i.p. injection;<5?μmol/kg) or water exposure (<50?nM) caused a 2–7 fold increase in hepatic EROD activity[2]. |
| In vivo | In rat models, Medetomidine exhibits dose-dependent sedative and analgesic effects. High doses (>100 μg/kg) can result in loss of righting reflex and hypothermia[3]. In anesthetized rats, Medetomidine induces transient hypotension and bradycardia. In denervated rats, it shows potent vasopressor activity (PD?? = 1.7 μg/kg) and suppresses sympathetic nerve activity (ID?? = 1.6 μg/kg)[3]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 200 mg/mL (998.6 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble), Sonication is recommended. |
| Keywords | Medetomidine |
| Inhibitors Related | Olanzapine | Mirtazapine | Octopamine hydrochloride | Gemfibrozil | Buflomedil hydrochloride | Tolazoline hydrochloride | Dexmedetomidine hydrochloride | Phenylephrine hydrochloride | Amitriptyline hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride | Doxepin hydrochloride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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