MAO-IN-M30 dihydrochloride NEW
| Price | $30 | $63 | $97 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: MAO-IN-M30 dihydrochloride | CAS No.: 64821-19-8 |
| Purity: 98.43% | Supply Ability: 10g |
| Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | MAO-IN-M30 dihydrochloride |
| 描述 | MAO-IN-M30 dihydrochloride (M 30 dihydrochloride) is a potent and brain selective monoamine oxidase (MAO) inhibitor (EC50 values are 37 and 57 nM for MAO-A and MAO-B, respectively). Also an iron chelator with antioxidant properties. Protects cells against 6-OHDA induced apoptosis. Attenuates MPTP depletion of DA and increases striatal monoamine levels in a mouse Parkinson's disease model. |
| 體外活性 | MAO-IN-M30 (0.25 nM; 72 hours) significantly increased cell viability to ~90% after exposure to Dexamethasone and reduced the occurrence of fragmented DNA compared to the dexamethasone-treated group in SH-SY5Y cells[3]. Additionally, MAO-IN-M30 (0-10 μM; 24 hours) enhances PC12 cell survival[4]. |
| 體內(nèi)活性 | MAO-IN-M30 (0.5-2.5 mg/kg; p.o.; once daily for 14 consecutive days) exhibits neuroprotective activities [6]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 1.8 mg/mL (6 mM), Sonication and heating to 60℃ are recommended. |
| 關(guān)鍵字 | M 30 Dihydrochloride | M 30 | MAO-IN-M30 | M-30 Dihydrochloride | M30 | M-30 | MAO-IN-M30 Dihydrochloride | M30 Dihydrochloride |
| 相關(guān)產(chǎn)品 | Norharmane | J-147 | Azure B | Iproniazid Phosphate | Paeonol | Isatin | Methylene Blue | Pargyline hydrochloride | Methylene Blue trihydrate | Phenelzine sulfate | Pargyline | Bifemelane hydrochloride |
| 相關(guān)庫 | 神經(jīng)退行性疾病化合物庫 | 經(jīng)典已知活性庫 | 神經(jīng)信號(hào)分子庫 | 抗抑郁癥化合物庫 | 抗氧化化合物庫 | 抑制劑庫 | 神經(jīng)保護(hù)化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 共價(jià)抑制劑庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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