We Offer Natural Centella asiatica extract Madecassic acid

We offer 100% Natural Centella asiatica extract Madecassic acid

Product Name: Madecassic acid

Specificaton: >80%

Form: Powder

Grade: Medicine grade 

Color: white

Shelf life: 2 years 

Loss on drying: 5%MAX

GMO-FREE

BSE/TSE FREE

ALLERGEN FREE

PESTICIDES FREE

ISO9001 Certified

Third Party Test Available

Paperwork Supported

Plant Audition Accepted

Prompt and Secure Shipment

Clean label

Madecassic acid is a triterpenoid that has been found in C. asiatica and has diverse biological activities. It inhibits LPS-induced production of nitric oxide (NO), prostaglandin E2 (PGE2; ), TNF-α, IL-1β, and IL-6 in RAW 264.7 macrophages when used at a concentration of 150 μg/ml. Madecassic acid (0.05 and 0.1% in the diet) decreases plasma levels of fibrinogenin and triglycerides, as well as heart and kidney levels of reactive oxygen species (ROS), in a mouse model of diabetes induced by streptozotocin (STZ; ). It decreases tumor growth in a CT26 murine colon cancer model in a dose-dependent manner.

We offer natural Madecassic acid, clean label Madecassic acid.

Anti-bacterial and anti-inflammation

Centella Asiatica Extract has a certain inhibitory effect on pseudomonas aeruginosa, staphylococcus aureus and acne bacillus. Asiatic acid can dissolve the bacteria’s outer waxy membranes and is killed by other drugs or body defense tissues. Asiatic acid and asiaticoside are available for external use to promote wound healing, and stimulate the development of granulation tissue. It can promote cutin or epidermal regeneration. It helps to form connective tissue. It is better to use with phospholipids. Centella Asiatica Extract has obvious effect of eliminating facial whelk and acne. Centella Asiatica Extract can reduce the production of pro-inflammatory mediators (IL-1, MMP-1). It improves and repairs the skin’s barrier function. Thereby it can prevent and correct the skin’s immune dysfunction. Therefore, Centella Asiatica Extract, due to its anti-inflammatory activity, can also be used in cosmetics such as after-sun repair and anti-allergic products.

Whitening

Centella Asiatica Extract also has strong antioxidant effect. It can inhibit free radical activity, and weaken melanin pigmentation. It improves skin blood circulation, and updates skin cell regeneration. Also it helps melanin metabolize out of the body smoothly. Skin will become smooth, delicate and white after using cosmetics containing Centella Asiatica Extract.

Repairing scars

Scientific research has found that Centella Asiatica Extract can promote the synthesis of collagen Ⅰ and Ⅲ. At the same time, it also can promote mucoitin secretion (such as the synthesis of hyaluronic acid); it increases skin moisture-retaining ability; it activates and renews skin cells. Other studies have showed that Centella Asiatica Extract also can activate fibroblast gene. It can enhance the activity of the basal layer cells of the skin; it maintains the elasticity and tightness of skin; and it smoothes fine wrinkles of face. Because of its important role in promoting collagen synthesis, angiogenesis and granulation growth in the body, Centella Asiatica Extract is conducive to wound healing, scar repair. It prevents striae gravidarum during pregnancy.

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Binbo Biological Co., Ltd. is located in the convenient transportation and beautiful scenery of Jining high-technology industrial zone - Jinxiang economic Development Zone. There is a 105 National road links north and south when Zaocao and Dongfeng Roads connect east and west. Besides, provincial expressway and Ji-Xu expressway which connect Beijing,Shanghai,Fuzhou, and several cities across the JinXiang economic development zone. More importantly, there are only 20 km to Jining airport and close to Qufu high-speed railway station.These convenient geographical conditions bring the development opportunities for this economic development zone.

Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products. Company was established in 2001, currently our company has more than 28 thousand square meters covering area. Factory buildings and workshops were establishsd by modern production requirements.There are three steps of development project which planned to invest around 60 million RMB. Currently the first step were finished and spent 28 million RMB, which met the production and office requirements.

Binbo is engaged in R&D with perfect equipments and advanced detecting instruments. The factory is in strict accordance with GMP standard in the course of design and construction.