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Postion:Product Catalog >m-PEG12-amine
m-PEG12-amine
  • m-PEG12-amine

m-PEG12-amine NEW

Price $39 $80 $128
Package 10mg 25mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: m-PEG12-amine CAS No.: 1977493-48-3
Purity: 100% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Namem-PEG12-amine
Descriptionm-PEG12-amine is a PEG-based PROTAC linker and a non-cleavable 12-unit PEG ADC linker used in the synthesis of PROTACs [1] and antibody-drug conjugates (ADCs) [2].
In vitroPROTACs, or proteolysis-targeting chimeras, are composed of two distinct ligands joined by a linker. One of these ligands binds to a specific protein target, while the other binds to an E3 ubiquitin ligase. When the PROTAC binds to both the target protein and the E3 ligase, it triggers the ubiquitin-proteasome system within cells to degrade the target protein, thereby providing a mechanism for targeted protein degradation.
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 90.0 mg/mL (160.8 mM), Sonication is recommended.
KeywordsmPEG12amine | m-PEG12-amine | m-PEG-12-amine | m PEG12 amine
Inhibitors RelatedSuccinic anhydride | DSS Crosslinker | Val-cit-PAB-OH | Fmoc-8-amino-3,6-dioxaoctanoic acid | Fmoc-Gly-Gly-OH | SMCC | Boc-NH-PEG4-CH2COOH | EMCS | DSG Crosslinker | FMoc-Val-Cit-PAB-PNP

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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