LY3437943 NEW
| Price | $300 | $600 |
| Package | 10mg | 20mg |
| Min. Order: | 10mg |
| Supply Ability: | 10000t |
| Update Time: | 2024-07-02 |
Product Details
| Product Name: LY3437943 | CAS No.: 2381089-83-2 |
| Min. Order: 10mg | Purity: 99% |
| Supply Ability: 10000t | Release date: 2024/07/02 |
LY3437943(subcutaneous injection; 0.47 mg/kg; Single-dose) is involved in GCGR in vivo and can improve glucose tolerance in ipGTT through GIP or GLP-1 receptors [1]. LY3437943(subcutaneous injection; 10 mL/kg; Cycle once every 3 days; For 21 days) causes substantial weight loss and increased energy expenditure through glucagon receptor activation [1]. LY3437943 is safe and tolerable [1]. Animal model: Male CD-1 mice [1] Dose: 0.47 mg/kg Administration: subcutaneous administration, single result: AUC0-∞, ng*h/mL Cmax,ng/mL Tmax,h t1/2,h CLF,mL/h/kg 41135 41905 1680 12 21 11.22 Animal model: Diet-induced obesity (DIO) male C57/Bl6 mice (24-25 weeks,40-51 g)[1] Dose: 10 mL/kg Administration: Subcutaneous injection (SC) every 3 days for 21 days. Results: Weight loss and blood glucose control improved.
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China- Since: 2022-08-09
- Address: Haiyue Tiandi, No. 66, Yuhua West Road, Shijiazhuang City, Hebei Province C1503