Lumbrokinase can be used to prevent and treat thrombotic and thrombotic diseases, as well as to treat patients with increased fibrinogen and platelet aggregation rates in ischemic cerebrovascular diseases. It has a significant effect on the recovery of limb paralysis and speech disorders in cerebrovascular diseases. It can be used for the treatment of transient ischemic attacks and early cerebral thrombosis, as well as for the prevention of cerebral thrombosis. It can also be used for the treatment of coronary heart disease, sudden deafness due to myocardial infarction, retinitis, central venous obstruction, pulmonary infarction, peripheral vascular embolism, etc.