Lisinopril Dihydrate NEW
Price | Get Latest Price |
Package | 1kg |
Min. Order: | 1kg |
Supply Ability: | 20tons |
Update Time: | 2024-04-08 |
Product Details
Product Name: Lisinopril Dihydrate | CAS No.: 83915-83-7 |
EC-No.: 627-033-9 | Min. Order: 1kg |
Purity: 99% | Supply Ability: 20tons |
Release date: 2024/04/08 |
Lisinopril is a third-generation angiotensin-converting enzyme inhibitor and a lysine derivative of enalapril. It was marketed in the United States in 1987 for the treatment of hypertension and is a first-line antihypertensive drug . The pharmacological action characteristics are similar to Enalapril (Enalapril), with strong angiotensin-converting enzyme inhibitory effect, quick onset and long action time, just take the medicine once a day. The inhibitory effect on ACE is 6 to 8 times that of captopril and 1 to 3 times that of benazepril.
Function and Application
Angiotensin Converting Enzyme Inhibitor (ACE-I), a lysine derivative of Enalapril, is the third non-sulfhydryl group in the world to be marketed. ACE-I. Long-acting, once a day, and the dosage is only 1/20 of captopril, 1/4 of enalapril, oral bioavailability is better. The curative effect is remarkable. For moderate and severe patients, the Chemicalbook should be better than captopril and enalapril. It has no direct effect on the heart, does not cause arrhythmia, has no central effect, and has no adverse reactions such as blood pressure rebound. It can be used for diseases accompanied by diabetes, asthma, peripheral vascular disease, psychosis and congestive heart failure, and for other diseases Patients with hypertension who are contraindicated in the treatment of drugs. It is effective for short-term and long-term congestive heart failure.
Product Name | Lisinopril dlhydrate | ||
Reference | USP | ||
Test | Specification | Results | |
Characters | White crystalline powder. | White crystalline powder. | |
Identification | 1) Infrared absorption spectrum concordant with spectrum obtained with Lisinopril dihydrate RS. | Conform | |
2) The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that of the Standard preparation obtained as directed in the Assay. | Conform | ||
Specific optical rotation [a]Hg25 | -115.3-122.5° | -119.6° | |
Water | 8.0~9.5% | 8.3% | |
Residue on ignition | ≤0.1% | <0.1% | |
Assay (HPLC) | 98.0-102.0% (calculated on anhydrous basis) | 98.6% | |
Residual solvents | Ethanol≤0.5% | 0.017% | |
Related substances (HPLC) | DL-Homophenylalanine ≤0.30% | <RL(RL:0.05%) | |
Related compound A ≤0.3% | <RL(RL:0.05%) | ||
R,S,S-Diketopiperazine ≤0.3% | <LOD(LOD:0.01%) | ||
Lisinopril epimer ≤0.3% | 0.07% | ||
Lisinopril cyclohexyl analogue ≤0.30% | 0.08% | ||
N-Alkyl-L-lysine ≤0.3% | 0.09% | ||
N-Alkyl lisinopril ≤0.15% | <LOD(LOD:0.01%) | ||
Any individual unspecified impurity≤0.10% | <RL(RL:0.05%) | ||
Total imp. does not include lisinopril epimer≤0.5% | 0.17% | ||
Conclusion | Complies with USP |
Company Profile Introduction
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$57.00/500mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
$57.00/500mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
$0.00/1KG |
VIP1Y
|
Hangzhou Hyper Chemicals Limited
|
2024-09-14 | |
$30.00/10g |
VIP1Y
|
hebei hongtan Biotechnology Co., Ltd
|
2024-05-15 | |
$36.00/1kg |
VIP2Y
|
Henan Fengda Chemical Co., Ltd
|
2024-04-16 | |
$0.00/1kg |
VIP2Y
|
Hangzhou ICH Biofarm Co., Ltd
|
2023-06-27 | |
$1.00/1g |
VIP6Y
|
Shanghai Longyu Biotechnology Co., Ltd.
|
2022-01-18 | |
$15.00/1KG |
Zhuozhou Wenxi import and Export Co., Ltd
|
2021-07-10 | ||
$380.00/25KG |
VIP4Y
|
Baoji Guokang Bio-Technology Co., Ltd.
|
2021-06-22 | |
$0.00/1Kg/Bag |
VIP4Y
|
WUHAN FORTUNA CHEMICAL CO., LTD
|
2021-06-15 |