Lincomycin hydrochloride
| Price | $10 |
| Package | 1kg |
| Min. Order: | 1kg |
| Supply Ability: | Ex 20 tons |
| Update Time: | 2022-10-22 |
Product Details
| Product Name: Lincomycin hydrochloride | CAS No.: 859-18-7 |
| EC-No.: 212-726-7 | Min. Order: 1kg |
| Purity: 99% | Supply Ability: Ex 20 tons |
| Release date: 2022/10/22 |
Use of Lincomycin hydrochloride
Lincomycin Hydrochloride(U10149A) is an antibiotic produced by Streptomyces lincolnensis var. lincolnensis.Target: AntibacterialLincomycin hydrochloride is a systemic antibiotic, which is active against most common gram positive bacteria. It has proved to be excellent for infectious diseases like acne, anthrax, pneumonia, and also for the treatment of furunculosis, carbuncles, impetigo, burns and wounds, carrying to gram positive bacteria. Lincomycin hydrochloride inhibits cell growth and microbial protein synthesis, by interacting strongly and specifically with the 50S ribosomal subunit, at mutually related sites
| Name | Lincomycin hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Lincomycin Hydrochloride(U10149A) is an antibiotic produced by Streptomyces lincolnensis var. lincolnensis.Target: AntibacterialLincomycin hydrochloride is a systemic antibiotic, which is active against most common gram positive bacteria. It has proved to be excellent for infectious diseases like acne, anthrax, pneumonia, and also for the treatment of furunculosis, carbuncles, impetigo, burns and wounds, carrying to gram positive bacteria. Lincomycin hydrochloride inhibits cell growth and microbial protein synthesis, by interacting strongly and specifically with the 50S ribosomal subunit, at mutually related sites [1-3]. |
|---|---|
| Related Catalog | Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection |
| Solvent | In Vitro: 10 mM in DMSO |
| Solubility | 1 mM2.2573 mL11.2867 mL22.5734 mL5 mM0.4515 mL2.2573 mL4.5147 mL10 mM0.2257 mL1.1287 mL2.2573 mL |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere |
| SMILES | C[C@@H](O)[C@@]([C@@]([C@@H]([C@H](O)[C@H]1O)O)([H])O[C@@H]1SC)([H])NC([C@@H]2C[C@@H](CCC)CN2C)=O.Cl |
| References | [1]. Griaznova, N.S., et al., [Effect of lincomycin and other protein synthesis inhibitors on the metabolism of Actinomyces roseolus, a producer of lincomycin]. Antibiotiki, 1980. 25(4): p. 250-6. [2]. Hummel, H., W. Piepersberg, and A. Bock, Analysis of lincomycin resistance mutations in Escherichia coli. Mol Gen Genet, 1979. 169(3): p. 345-7. [3]. Champney, W.S. and C.L. Tober, Specific inhibition of 50S ribosomal subunit formation in Staphylococcus aureus cells by 16-membered macrolide, lincosamide, and streptogramin B antibiotics. Curr Microbiol, 2000. 41(2): p. 126-35. |
| Related Molecules | Puromycin dihydrochloride | Geneticin | Tunicamycin | Hygromycin B | Salinomycin | Avibactam sodium | Neomycin sulfate | Vaborbactam | Methicillin SodiuM | Rifampicin | Metronidazole | Carbenicillin disodium | Ceftazidime | Eravacycline dihydrochloride | cefotaxime sodium |
| Boiling Point | 646.8oC at 760 mmHg |
|---|---|
| Melting Point | 156-158oC |
| Molecular Formula | C18H35ClN2O6S |
| Molecular Weight | 442.998 |
| Flash Point | 345oC |
| Exact Mass | 442.190430 |
| PSA | 147.79000 |
| LogP | 0.27380 |
| Storage condition | 2-8°C |
| Water Solubility | H2O: 50 mg/mL, clear, colorless | Soluble in water |
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