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Postion:Product Catalog >API>Antiallergic drugs>Antihistamines>Levocetirizine dihydrochloride
Levocetirizine dihydrochloride
  • Levocetirizine dihydrochloride
  • Levocetirizine dihydrochloride
  • Levocetirizine dihydrochloride

Levocetirizine dihydrochloride

Price $40
Package 1KG
Min. Order: 1KG
Supply Ability: Ex 20 tons
Update Time: 2022-09-15

Product Details

Product Name: Levocetirizine dihydrochloride CAS No.: 130018-87-0
EC-No.: 641-093-3 Min. Order: 1KG
Purity: 99% Supply Ability: Ex 20 tons
Release date: 2022/09/15
Levocetirizine dihydrochloride Usage And Synthesis
UsesAnti Histaminic
UsesLevocetirizine dihydrochloride has been used as standard in the thin layer chromatography optimization and in preparation of racemic cetirizine standard for subcritical fluid chromatography-tandem mass spectrometry analysis.
General DescriptionLevocetirizine dihydrochloride,(R)-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl] ethoxy] acetic acid dihydrochloride, (Xyzal) is awhite, crystalline powder and is water soluble. ThisR-enantiomer is has a 30-fold higher affinity than the S-enantiomer,and dissociates more slowly from H1-receptors.Pharmacologically, it displays the same receptor and CNSselecitivity profile as the racemate, cetirizine,and thus the same therapeutic advantages. Levocetirizine isindicated for the relief of symptoms associated with allergicrhinitis (seasonal and perennial) in adults and children 6 yearsof age and older and for the treatment of the uncomplicatedskin manifestations of chronic idiopathic urticaria in adultsand children 6 years of age and older. Its pharmacokineticsand clearance profile are essentially the same as the racemate,cetirizine .
Biochem/physiol ActionsLevocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.



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  • Since: 2022-02-24
  • Address: 3-1-1005, Federal Business Plaza, 166 Yuhua West Road, Qiaoxi District, Shijiazhuang City, Hebei Pro
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