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Postion:Product Catalog >API>Antineoplastic agents>Hormonal antineoplastic drugs>Letrozole
Letrozole
  • Letrozole
  • Letrozole
  • Letrozole
  • Letrozole
  • Letrozole

Letrozole NEW

Price $25
Package 1box
Min. Order: 1box
Supply Ability: 10000box
Update Time: 2024-05-15

Product Details

Product Name: Letrozole CAS No.: 112809-51-5
EC-No.: 1806241-263-5 Min. Order: 1box
Purity: 99% Supply Ability: 10000box
Release date: 2024/05/15

Chinese name: Letrozole

English name: Letrozole

CAS: 112809-51-5

Molecular formula: C17H11N5

MDL number: MFCD00866241

Molecular weight: 285.3

Appearance: White or white powder

Appearance: Melting point 181 ~ 183℃

Melting point: 181-183°C

Boiling point: 563.5±60.0 °C(Predicted)

Density: 1.21± 0.1g /cm3(Predicted)

Storage conditions: 2-8°C

Solubility: dimethyl sulfoxide: >50mg/mL

Acidity coefficient (pKa) : 1.52±0.11(Predicted)

Form: White powder

Color: White to off-white

Merck: 14,5450

InChI: InChI = 1 s/C17H11N5 / c18-9-13-1-5-15 17 (22-12-20-22-12-20) (6-2-13) 16-7-3-14 (10-19)/h1-4-8-16 8, 11-12 H

InChIKey: HPJKCIUCZWXJDR-UHFFFAOYSA-N

SMILES: C (C1 = CC = C (C = C1) C # N) (C1 = CC = C (C = C1) C # N) N1C = NC = N1

Use 1

Pyrrole aromatization enzyme inhibitors. Used to treat breast cancer.

Preparation method

4-bromomethyl benzonitrile (I) reacts with triazole in chloroforme-acetonitrile, and the resulting product (II) reacts with 4-fluoronitrile in dimethylformamide in the presence of potassium tert-butanol to obtain letrozole.


Company Profile Introduction

Shanghai Getian Industrial Co.,Ltd is a leading enterprise committed to providing quality products and efficient logistics services. We are proud to introduce a range of products with excellent quality, and the industrial materials are subject to strict quality control to ensure that the high standards of our customers are met. We have pharmaceutical raw material production factory and reagent research and development center. We now have a complete product line. In addition, we have developed and produced tens of thousands of reagents. We are complemented by a custom synthesis business of various organic compounds. We can synthesize almost any chemical.

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