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Postion:Product Catalog >Biochemical Engineering>Inhibitors>protein tyrosine kinase>Lenvatinib
Lenvatinib
  • Lenvatinib
  • Lenvatinib

Lenvatinib

Price Get Latest Price
Package 1g 5g 10g
Min. Order: 1g
Supply Ability: 1000
Update Time: 2025-01-16

Product Details

Product Name: Lenvatinib CAS No.: 417716-92-8
Min. Order: 1g Purity: 98
Supply Ability: 1000 Release date: 2025/01/16

Product Name:    Lenvatinib

Synonyms:    4-[3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinolinecarboxamide;E7080;LENVATINIB;E7080 (Lenvatinib);Lenvatinib (E7080);ER-203492-00;1-(4-(6-carbamoyl-7-methoxyquinolin-4-yloxy)-2-chlorophenyl)-3-cyclopropylurea;4-[3-Chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6-quinolinecarboxamide XEN445

CAS:    417716-92-8

MF:    C21H19ClN4O4

MW:    426.85

EINECS:    1592732-453-0

Product Categories:    API;Inhibitors;FGF receptor antagonist;417716-92-8;Intermediate

Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRα, PDGFRβ and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces tumor growth in an H146 small cell lung cancer mouse xenograft model and induces tumor regression when administered at a dose of 100 mg/kg twice per day. Formulations containing lenvatinib have been used in the treatment of differentiated thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma.


Company Profile Introduction

Wuhan Circle Star Chem-medical Technology Co.,Ltd is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in electronic chemicals, pharmaceutical intermediates, pesticide intermediates, ultraviolet absorbent, food additives and other fine chemical products research and development, production, sales and operation or agency of various products and technology import and export business. The company has two laboratories (located in wuhan and ningbo), a Chinese workshop (located in wuhan), and two amplification production bases (located in zhejiang and hubei).The company employs a number of postdocs, doctors and professors from wuhan university, huazhong agricultural university, huazhong university of science and technology and other famous universities in China to form the r&d team, and also has its own excellent sales team. The company always adhere to the "technology first, customer first, quality after-sales service" professional philosophy and enterprise spirit.The company can provide excellent products, technical support and perfect after-sales service, and ensure the quality and timely delivery regardless of business size.In order to establish a good reputation among domestic and foreign customers.

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  • Since: 2024-03-12
  • Address: Room 02-31, 13 / F, Building 9, Guannan Fuxing Medical Park Phase II, No.58, Guanggu Avenue, East La
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