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Postion:Product Catalog >Lenumlostat
Lenumlostat
  • Lenumlostat

Lenumlostat NEW

Price $197 $497 $747
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Lenumlostat CAS No.: 2098884-52-5
Purity: 99.88% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameLenumlostat
DescriptionLenumlostat is an orally available, selective and potent lysyl oxidase-like protein 2 (LOXL2) inhibitor with inhibitory effects on hLOXL2, hLOXL3 and LOXL2 for the study of fibrotic diseases.
In vitroLenumlostat(PAT-1251)is a Lysyl Oxidase-Like 2 (LOXL2) inhibitor, with IC50s of 0.71 μM and 1.17 μM for hLOXL2 and hLOXL3, respectively. It also potently inhibits LOXL2 in mouse, rat, and dog, with IC50s of 0.10 μM, 0.12 μM, and 0.16 μM, respectively. Lenumlostat(PAT-1251) exhibits high selectivity for LOXL2 over other key members of the amine oxidase family, such as the copper-dependent amine oxidases semicarbazide-sensitive amine oxidase (SSAO) and diamine oxidase (DAO). Additionally, it shows selectivity against the flavin-dependent monoamine oxidases A (MAO-A) and B (MAO-B), with less than 10% inhibition at 10 μM[1].
Storagestore under nitrogen | Shipping with blue ice.
Solubility InformationDMSO : 45 mg/mL (112.69 mM), Sonication is recommended.
H2O : 80 mg/mL (200.33 mM)
Inhibitors RelatedNorharmane | J-147 | Azure B | Iproniazid Phosphate | Paeonol | Isatin | Methylene Blue | Pargyline hydrochloride | Methylene Blue trihydrate | Phenelzine sulfate | Pargyline | Bifemelane hydrochloride
Related Compound LibrariesBioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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