Product Details
Product Name:
LDCA |
CAS No.:
349106-80-5 |
Purity:
98.99% |
Supply Ability:
10g |
Release date:
2024/11/16 |
Product Introduction
Bioactivity
名稱 | LDCA |
描述 | LDCA is a double-hit metabolic regulator that exhibits potent anti-proliferative activity. lDCA competitively inhibits LDH-A enzyme activity, alters mitochondrial hyperpolarization and simultaneously subverts apoptosis. lDCA has a pronounced effect in cancer cells and does not show toxicity. |
體外活性 | LDCA (2-100 μM ; 16-72 h) and Doxorubicin combination synergistically inhibit tumor progression. 15% death when cells were exposed to LDCA individually and caused 40% melanoma cell death combination synergistically with doxorubicin.[1] |
體內(nèi)活性 | LDA (2 mg/kg, iv., 6 days ; once) combination with doxorubicin effectively alleviated tumor necrosis in mice and significantly improved their survival ability, leading to sustained limitations in tumor growth kinetics.[1] |
存儲(chǔ)條件 | Shipping with blue ice. |
溶解度 | DMSO : 90.0 mg/mL (350.9 mM ), Sonication and heating to 60℃ are recommended.
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相關(guān)產(chǎn)品 | Stavudine | 5-Fluorouracil | Acetylcysteine | Kaempferol | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin | Lidocaine hydrochloride |
相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 | 抗癌化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |