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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Endocrinology & Hormones>RAAS inhibitors>LCZ696
LCZ696
  • LCZ696
  • LCZ696
  • LCZ696

LCZ696

Price Get Latest Price
Package 1kg 5kg 10kg
Min. Order: 1kg
Supply Ability: 1000
Update Time: 2025-01-15

Product Details

Product Name: LCZ696 CAS No.: 936623-90-4
Min. Order: 1kg Purity: 98
Supply Ability: 1000 Release date: 2025/01/15

Product Name:    LCZ696

Synonyms:    Entresto;LZC696;[(C24H29N5O3).(C24H29NO5).2.5(H2O).3Na];LCZ696 ENTRESTO TM;LCZ696 Entresto;4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate;Sacubitril mixture with Valsartan;Cocrystal of Sacubitril and Valsartan

CAS:    936623-90-4

MF:    C48H58N6O8

MW:    847.03

EINECS:    000-000-0

Product Categories:    Cardiovascular Series;Inhibitors;API;936623-90-4

LCZ696 is a dual angiotensin II receptor antagonist and neprilysin inhibitor that is a combination of the nonpeptide angiotensin II receptor antagonist valsartan and AHU377 , a prodrug of LBQ657 , which is an inhibitor of the zinc metallopeptidase neprilysin., LCZ696 (2-60 mg/kg) induces a dose-dependent decrease in mean arterial pressure in rats expressing human renin and angiotensinogen, a double-transgenic model for angiotensin II-dependent hypertension. Formulations containing LCZ696 are under clinical investigation for the treatment of mild to moderate hypertension and chronic heart failure.


Company Profile Introduction

Wuhan Circle Star Chem-medical Technology Co.,Ltd is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in electronic chemicals, pharmaceutical intermediates, pesticide intermediates, ultraviolet absorbent, food additives and other fine chemical products research and development, production, sales and operation or agency of various products and technology import and export business. The company has two laboratories (located in wuhan and ningbo), a Chinese workshop (located in wuhan), and two amplification production bases (located in zhejiang and hubei).The company employs a number of postdocs, doctors and professors from wuhan university, huazhong agricultural university, huazhong university of science and technology and other famous universities in China to form the r&d team, and also has its own excellent sales team. The company always adhere to the "technology first, customer first, quality after-sales service" professional philosophy and enterprise spirit.The company can provide excellent products, technical support and perfect after-sales service, and ensure the quality and timely delivery regardless of business size.In order to establish a good reputation among domestic and foreign customers.

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