Lanicemine dihydrochloride NEW
| Price | $30 | $48 | $85 |
| Package | 2mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-20 |
Product Details
| Product Name: Lanicemine dihydrochloride | CAS No.: 153322-06-6 |
| Purity: 99.43% | Supply Ability: 10g |
| Release date: 2024/11/20 |
Product Introduction
Bioactivity
| Name | Lanicemine dihydrochloride |
| Description | Lanicemine dihydrochloride (AZD-6765 dihydrochloride) is a low-capture NMDA channel blocker with antidepressant activity and can be used to study neurological diseases. |
| In vivo | The levels of the GluA1 subunit of AMPA receptors, synapsin I, BDNF, and CREB after treatment of mice with either hyperforin or Lanicemine dihydrochloride or a combination of both drugs. This treatment strategy did not significantly alter p-CREB/CREB levels but elevated BDNF in the frontal cortex (1 h after hyperforin and 1.5 h after Lanicemine dihydrochloride administration). A single dose of either hyperforin or Lanicemine dihydrochloride did not alter the expression of synapsin I and GluA1. In contrast, the combined administration of hyperforin and Lanicemine dihydrochloride increased the levels of both proteins. After 72 h, a combination of hyperforin and Lanicemine dihydrochloride did not alter p-CREB/CREB levels; however, Lanicemine dihydrochloride and hyperforin + Lanicemine dihydrochloride significantly increased the levels of BDNF in the test animals compared to controls. The levels of other proteins (synapsin I, GluA1) remained unchanged 72 h after treatment. [1] |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Inhibitors Related | (-)-Aspartic acid | Mephenesin | Quinolinic acid | Halothane | Riluzole | Ifenprodil Tartrate | Bupivacaine hydrochloride monohydrate | MRZ 2-514 | O-Phospho-L-serine | Procaine hydrochloride | Memantine hydrochloride | UBP551 |
| Related Compound Libraries | Drug Repurposing Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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