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Postion:Product Catalog >L82
L82
  • L82

L82 NEW

Price $64 $105 $197
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: L82 CAS No.: 329227-30-7
Purity: 99% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameL82
DescriptionL82 is a DNA ligase 1 (DNA Lig1) inhibitor (hLig1 IC50=12 μM) that is selective and non-competitive.L82 expresses anti-proliferative activity against breast cancer cells.
In vitroL82 (0-50 μM; 6 d) reduced the proliferation of a normal breast epithelial cell line MCF10A and the breast cancer cell lines MCF7, HeLa, and HCT116 in a concentration-dependent manner.[2] L82 (50 μM; 0-48 h) shows cytostatic activity due to activation of the G1/S checkpoint in MCF7 cells.[2]' Revised: L82 (0-50 μM; 6 d) concentration-dependently reduced proliferation in the normal breast epithelial cell line MCF10A and the breast cancer cell lines MCF7, HeLa, and HCT116, while L82 (50 μM; 0-48 h) exhibited cytostatic activity through activation of the G1/S checkpoint in MCF7 cells.[2]
StorageShipping with blue ice.
Solubility InformationDMSO : 6 mg/mL (19.38 mM), Sonication is recommended.
Inhibitors RelatedNorharmane | Cyclophosphamide hydrate | Quinacrine dihydrochloride | Proflavine Hemisulfate | Chromium picolinate | Clofazimine | Hydroxychloroquine sulfate | Methoxsalen | Carboxy-pyridostatin 2HCl | Tallimustine HCl | Cyclophosphamide | Crystal Violet
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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