L-Propargylglycine NEW
Price | Get Latest Price | ||
Package | 1kg | 10kg | 100kg |
Min. Order: | 1kg |
Supply Ability: | 1T+ |
Update Time: | 2024-12-23 |
Product Details
Product Name: L-Propargylglycine | CAS No.: 23235-01-0 |
Min. Order: 1kg | Purity: 98% |
Supply Ability: 1T+ | Release date: 2024/12/23 |
Product Name: | L-Propargylglycine |
CAS: | 23235-01-0 |
MF: | C5H7NO2 |
MW: | 113.11 |
Synonyms: | (2R)-2-Aminopent-4-ynoic acid;(S)-2-AMINO-4-PENTYNOIC ACID;RARECHEM BK PT 0255;H-GLY(PROPARGYL)-OH;H-PRA-OH;H-PRA-OH HCL;H-PROPARGYL-GLYCINE;H-PROPARGYL-GLY-OH |
Product Categories: | Amino Acid Derivatives; Amino Acid Esters |
Application: | Inhibitor of Cystathionine γ-Synthase (CBS): L-Propargylglycine is commonly used as an inhibitor of CBS, an enzyme involved in the transsulfuration pathway responsible for the biosynthesis of cysteine from homocysteine. Inhibition of CBS by propargylglycine can lead to decreased levels of cysteine and downstream metabolites, making it useful in studying sulfur metabolism and in the treatment of diseases related to abnormal sulfur metabolism. Bioorthogonal Chemistry: The propargyl functional group in L-Propargylglycine can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a widely used bioorthogonal chemical reaction. This reaction is used to selectively label biomolecules in complex biological systems, making propargylglycine a valuable tool in chemical biology and bioconjugation studies. Click Chemistry: L-Propargylglycine can be used as a substrate in click chemistry reactions, particularly in copper-free strain-promoted azide-alkyne cycloaddition (SPAAC) reactions. This reaction does not require copper catalysts and is compatible with biological systems, allowing for the specific labeling of biomolecules in live cells and organisms. |
Manufacturer: | Sichuan HongRi Pharma-Tech Co., Ltd. |
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- Since: 2021-03-30
- Address: A38-2, No. 66, Nanhu road, Deyang City, Sichuan Province (Jiuwei Blue Valley)