L-NMMA acetate NEW
| Price | $34 | $48 | $76 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: L-NMMA acetate | CAS No.: 53308-83-1 |
| Purity: ≥98% | Supply Ability: 10g |
| Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | L-NMMA acetate |
| 描述 | L-NMMA acetate (Tilarginine acetate) is an inhibitor of nitric oxide synthase of all NOS isoforms (i.e. NOS1, NOS2, and NOS3). The Ki values are 0.18, 0.4, and 6 μM for nNOS, eNOS, and iNOS, respectively. |
| 體外活性 | L-NMMA selectively inhibits vasodilator responses to endothelium-dependent ACh without affecting responses to endothelium-independent NP and does not alter isoprenaline-induced relaxation. Its inhibitory action remains unaffected by D-arginine but is countered by L-arginine (L-Arg). L-NMMA initiates a concentration-dependent decrease in vasodilation (2Hz) starting at 100 μM, achieving maximum inhibition around 35% at 1 mM. It reduces arteriolar diameter and increases arteriolar tone in a dose-dependent manner with an immediate onset of action. Moreover, L-NMMA significantly enhances NE-induced vasoconstriction. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | H2O : 50 mg/mL (201.39 mM) |
| 關鍵字 | Tilarginine Acetate | Tilarginine | Methylarginine | L-NMMA | NOS | Nitric oxide synthases | L NMMA acetate | inhibit | LNMMA acetate | L-NMMA Acetate | NO Synthase | Inhibitor | Methylarginine Acetate |
| 相關產(chǎn)品 | Miconazole | Aminoguanidine hydrochloride | L-NAME hydrochloride | EIT hydrobromide | 3-Bromo-7-nitroindazole | Dexamethasone acetate | S-Methylisothiourea sulfate | Cannabigerol | 1400W dihydrochloride | Flavone | S-(2-aminoethyl) Isothiourea (dihydrobromide) | Diallyl disulfide |
| 相關庫 | 經(jīng)典已知活性庫 | ReFRAME 相關化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 神經(jīng)保護化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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