L-Glutathione reduced NEW
Price | $32 |
Package | 1g |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: L-Glutathione reduced | CAS No.: 70-18-8 |
Purity: 99.97% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | L-Glutathione reduced |
Description | L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is involved in the rearrangement of protein disulfide bonds and the reduction of peroxides. |
In vitro | METHODS: NSCs cells were treated with L-Glutathione reduced (0.5 mM) and sevoflurane (3%) for 24 h. Apoptosis was detected using TUNEL staining. RESULTS: Supplementation with reduced L-Glutathione reduced the effect of sevoflurane on apoptosis of NSCs. [1] |
In vivo | METHODS: To study in vivo activity, L-Glutathione reduced (100 mg/kg) was administered orally to mice and GSH concentrations were measured in plasma at 30, 45, and 60 min, and in the liver, kidneys, heart, lungs, brain, small intestine, and skin 1 h later. RESULTS: Within 30 min of oral L-Glutathione reduced administration, plasma GSH concentrations increased from 30 μM to 75 μM, consistent with a rapid flow of GSH from the intestinal lumen to the plasma. Under these conditions of GSH sufficiency, GSH concentrations in most tissues did not exceed control values over the same time course, with the exception of lung. [2] |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | Shipping with blue ice. |
Solubility Information | DMSO : Insoluble, The compound is unstable in solution. Please use soon. H2O : 153.7 mg/mL (500 mM) |
Keywords | Inhibitor | Endogenous Metabolite | inhibit | r-L-Glutamyl-L-cysteinyl-glycine | L-Glutathione reduced | LGlutathione reduced | gamma-L-Glutamyl-L-cysteinyl-glycine | L Glutathione reduced | Ferroptosis | Reactive Oxygen Species |
Inhibitors Related | Sucrose | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Formamide | Oleamide | Glycerol | Thymidine | Naringin | Salicylic acid | Oxalic acid dihydrate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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