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Postion:Product Catalog >L-Clausenamide
L-Clausenamide
  • L-Clausenamide

L-Clausenamide NEW

Price $397 $970 $1580
Package 1mg 5mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: L-Clausenamide CAS No.: 201529-58-0
Purity: 99.28% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameL-Clausenamide
DescriptionL-Clausenamide is an alkaloid extracted from the leaves of the yellow bark (Clausena lansium (Lour) skeels) and can be used to improve cognitive function. L-Clausenamide inhibits beta-amyloid (Aβ) toxicity and prevents the formation of neurofibrillary tangles by inhibiting tau phosphorylation. L-Clausenamide has neuroprotective activity and can be used to modulate stimuli triggered by Aβ25-35. L-Clausenamide can be used to study neurological disorders like Alzheimer's disease.
In vitroReversing the overload in [Ca2+]i level stimulated by Aβ25-35 and reducing Aβ-mediated cell apoptosis in PC12 cells, L-Clausenamide (10 and 100 μM) demonstrates its protective effects[3]. In Aβ25-35-treated PC12 cells, L-Clausenamide (10 and 100 μM) inhibits the phosphorylation of p38 MAPK and down-regulates the expression of P53 and cleaved Caspase-3, as well as the ratio of Bax/Bcl-2[3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (168.15 mM)
KeywordsL-Clausenamide | Clausenamide
Inhibitors RelatedFlubendazole | Mebendazole | N-Phenylbenzylamine | 4-Isopropoxybenzoic acid | Oxfendazole | Thiabendazole | Methylene Blue | Methylene Blue trihydrate | Paclitaxel | 4'-Demethylepipodophyllotoxin
Related Compound LibrariesBioactive Compound Library | Traditional Chinese Medicine Monomer Library | Alkaloid Natural Product Library | Selected Plant-Sourced Compound Library | Natural Product Library | Natural Product Library for HTS | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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