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Postion:Product Catalog >KYP-2047
KYP-2047
  • KYP-2047

KYP-2047 NEW

Price $45 $64 $106
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: KYP-2047 CAS No.: 796874-99-2
Purity: 99.7% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameKYP-2047
DescriptionKYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.
In vitroIn cell lines, oxidative stress induced a robust aggregation of α-synuclein,and low concentrations of KYP-2047 significantly reduced the number of cells with α-synuclein inclusions while abolishing the colocalization of α-synuclein and PREP. KYP-2047 significantly reduced the amount of aggregated α-synuclein,and it had beneficial effects on cell viability.?In the transgenic mice, a 5-day treatment with the PREP inhibitor reduced the amount of α-synuclein immunoreactivity and soluble α-synuclein protein in the brain[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 25 mg/mL (73.65 mM)
KeywordseNOS | inhibit | POP | Neurotensin | Angiopoietins | MDM-2/p53 | KYP 2047 | prolyl oligopeptidase | Glioblastoma | KYP-2047 | VEGF | KYP2047 | Prolyl Endopeptidase (PREP) | Inhibitor | U-87 cell | Apoptosis
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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