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Postion:Product Catalog >KN-92 phosphate
KN-92 phosphate
  • KN-92 phosphate

KN-92 phosphate NEW

Price $64 $107 $178
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-04

Product Details

Product Name: KN-92 phosphate CAS No.: 1135280-28-2
Purity: 99.31% Supply Ability: 10g
Release date: 2024/11/04

Product Introduction

Bioactivity

名稱KN-92 phosphate
描述KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM).
體外活性KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cell.
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 55 mg/mL (99.1 mM)
關(guān)鍵字KN92 phosphate | derivative | inactive | KN 92 phosphate | KN 92 Phosphate | control | Inhibitor | KN-92 Phosphate | experimental | KN-92 | KN 92 | inhibit | KN92 | KN92 Phosphate | analog
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Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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