K-Ras ligand-Linker Conjugate 6 NEW
| Price | $124 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-18 |
Product Details
| Product Name: K-Ras ligand-Linker Conjugate 6 | CAS No.: 2378261-89-1 |
| Supply Ability: 10g | Release date: 2024/11/18 |
Product Introduction
Bioactivity
| 名稱 | K-Ras ligand-Linker Conjugate 6 |
| 描述 | K-Ras ligand-Linker Conjugate 6 is a chemical compound that combines a ligand for the K-Ras recruiting moiety and a PROTAC linker. It can recruit E3 ligases, including VHL, CRBN, MDM2, and IAP. K-Ras ligand-Linker Conjugate 6 is particularly useful in synthesizing PROTAC K-Ras Degrader-1, which achieves ≥70% degradation efficacy in SW1573 cells[1]. |
| 體外活性 | PROTACs consist of two ligands linked together: one targets an E3 ubiquitin ligase and the other the target protein, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| 存儲(chǔ)條件 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 關(guān)鍵字 | K Ras ligand Linker Conjugate 6 | KRas ligandLinker Conjugate 6 | K-Ras ligand-Linker Conjugate 6 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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