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Postion:Product Catalog >JR14a
JR14a
  • JR14a

JR14a NEW

Price $84 $198 $313
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: JR14a CAS No.: 2411440-41-8
Purity: 99.29% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameJR14a
DescriptionJR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.
In vitroIn vitro, thiophene compounds potently inhibited intracellular Ca2+ release in human macrophages without inhibiting the agonist effects in the same concentration range as the related Complement protein C5a[1].
In vivoJR14a reduces mast cell degranulation and macrophage infiltration in BR103-induced rat paw edema[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 90 mg/mL (168.71 mM), Sonication is recommended.
Keywordsinflammation | Inhibitor | inhibit | C3a | JR-14a | Complement System | JR14a | complement
Inhibitors RelatedEG01377 2HCl | Iptacopan hydrochloride | SB290157 trifluoroacetate | BCX 1470 hydrochloride | Complement C5-IN-1 | ADH-503 | CP-289 | Dexamethasone | CP-447697 | Complement factor D-IN-2 | Cyclosporin A | 3-Phenoxybenzaldehyde
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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