JC2-11 NEW
Price | $38 | $89 | $147 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-16 |
Product Details
Product Name: JC2-11 | CAS No.: 937820-89-8 |
Purity: 98.6% | Supply Ability: 10g |
Release date: 2024/11/16 |
Product Introduction
Bioactivity
名稱 | JC2-11 |
描述 | JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen species (ROS) production and caspase-1 activity.JC2-11 reduces caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) activity in inflammatory vesicles. JC2-11 reduced caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) release from inflammatory vesicles. |
體內(nèi)活性 | JC2-11 (250 μg/mouse; i.p.; single dose) significantly inhibited the release of caspase-1 (p20) and IL-1β from the non-canonical (NC) inflammasome in the C57BL/6 mouse model, attenuated NC inflammasome activation.[1] |
存儲條件 | Shipping with blue ice. |
溶解度 | DMSO : 90.0 mg/mL (297.7 mM) |
關(guān)鍵字 | JC211 | JC2-11 |
相關(guān)產(chǎn)品 | Stavudine | Inosine pranobex | Acetylcysteine | Rotenone | Mycophenolate Mofetil | Ribavirin | L-Arginine | Tempol | Lycopene | Ethyl cinnamate | Diallyl disulfide | Isomalt |
相關(guān)庫 | 經(jīng)典已知活性庫 | 抗衰老化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$5.00/1KG |
VIP1Y
|
Hebei Longbang Technology Co., Ltd
|
2024-05-13 | |
$50.00/1kg |
VIP2Y
|
Hebei Miaoyin Technology Co.,Ltd
|
2023-03-10 | |
$90.00/1kg |
VIP1Y
|
hebei hongtan Biotechnology Co., Ltd
|
2024-03-21 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY