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Postion:Product Catalog >API>Antiparasitic drugs>Antifilarial and Leishmaniasis Drugs>Ivermectin
Ivermectin
  • Ivermectin

Ivermectin NEW

Price $53
Package 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Ivermectin CAS No.: 70288-86-7
Purity: 97.74% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameIvermectin
DescriptionIvermectin (MK-933) is an activator of glutamate-gated chloride channels (GluCls) with antiparasitic activity.
In vitroIvermectin exhibits antiviral activity against HIV-1 and Dengue fever virus. It binds to a novel site on GABAA receptors in hippocampal embryonic neurons of mice, conformationally enhancing the affinity of the GABA binding site. In nematodes, the compound interacts with glutamate-gated chloride channels (GluCls), disrupting the regulation mediated by GluCl activity.
In vivoIntraperitoneal injection of Ivermectin (1.25-10 mg/kg) can reduce the consumption of alcohol and saccharin. For mice exposed to lethal doses of LPS, Ivermectin inhibits LPS-induced NF-kB translocation and enhances survival rates.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationEthanol : 27 mg/mL (30.9 mM)
DMSO : 45 mg/mL (51.42 mM)
H2O : < 1 mg/mL (insoluble or slightly soluble)
KeywordsSARS coronavirus | inhibit | Mitophagy | SARS-CoV | Autophagy | Antibiotic | MK933 | Human immunodeficiency virus | Ivermectin | HIV | Parasite | Inhibitor | Herpes simplex virus | Mitochondrial Autophagy | MK 933 | HSV
Related Compound LibrariesPesticide Compound Library | Anti-Parasitic Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Anti-Viral Compound Library | Natural Product Library for HTS | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
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