Isradipine NEW
| Price | $33 | $54 | $98 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Isradipine | CAS No.: 75695-93-1 |
| Purity: 99.84% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Isradipine |
| Description | Isradipine (PN 200-110) is a dihydropyridine calcium channel blocker with antihypertensive and vasodilator activities. Isradipine blocks calcium entry through calcium ion channels in coronary and peripheral vascular smooth muscle, dilating coronary arteries and peripheral arterioles. This action increases oxygen delivery by enhancing blood flow and decreases oxygen requirements by reducing total peripheral resistance. |
| In vitro | In vivo oxygen uptake (I50 = 31.1 mM) and growth incubation (I50 = 20.8 mM) assays showed that Isradipine was the most effective derivative. At micromolar concentrations, Isradipine inhibited oxygen consumption and growth incubation of the short-membrane form of Trypanosoma cruzi strain Tulahuen. |
| In vivo | In vivo oxygen uptake (I50 = 31.1 mM) and growth incubation (I50 = 20.8 mM) assays showed that Isradipine was the most effective derivative. At micromolar concentrations, Isradipine inhibited oxygen consumption and growth incubation of the short-membrane form of Trypanosoma cruzi strain Tulahuen. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : 7.4 mg/mL (20 mM) DMSO : 50 mg/mL (134.63 mM) |
| Keywords | vasodilator | channel | selective peripheral | Ca2+ channels | circulation | Autophagy | Parkinson's | dihydropyridine | inhibit | calcium | Calcium Channel | Inhibitor | powerful | neuroprotective | Isradipine | L-type | Ca channels | peripheral |
| Inhibitors Related | Stavudine | Sodium 4-phenylbutyrate | L-Ascorbic acid | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Paeonol | Naringin | Gefitinib |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Neuroprotective Compound Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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