Isatin NEW
| Price | Get Latest Price |
| Package | 25KG |
| Min. Order: | 1KG |
| Supply Ability: | 50000KG/month |
| Update Time: | 2023-08-26 |
Product Details
| Product Name: Isatin | CAS No.: 91-56-5 |
| EC-No.: 202-077-8 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: 50000KG/month |
| Release date: 2023/08/26 |
| CAS: | 91-56-5 |
| MF: | C8H5NO2 |
| MW: | 147.13 |
| EINECS: | 202-077-8 |
| Product Categories: | Heterocyclic Compounds;Indoles;Intermediates;Simple Indoles;91-56-5 |
| Mol File: | 91-56-5.mol |
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| Isatin Chemical Properties |
| Melting point | 193-195 °C (dec.) (lit.) |
| Boiling point | 267.22°C (rough estimate) |
| density | 1.3067 (rough estimate) |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.4700 (estimate) |
| Fp | 220 °C |
| storage temp. | Store below +30°C. |
| solubility | soluble |
| pka | 10.34±0.20(Predicted) |
| form | Powder |
| color | Orange |
| PH | 7 (1.9g/l, H2O, 20℃) |
| Water Solubility | Soluble in water (1.9 g/L at 20°C). |
| Decomposition | 194 oC |
| Merck | 14,5104 |
| BRN | 383659 |
| Stability: | Stable. Incompatible with strong acids. |
| InChIKey | JXDYKVIHCLTXOP-UHFFFAOYSA-N |
| LogP | 0.45 |
| CAS DataBase Reference | 91-56-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Isatin(91-56-5) |
| EPA Substance Registry System | 1H-Indole-2,3-dione (91-56-5) |
| Isatin Usage And Synthesis |
| Isatin | Isatin, is also known as indenedione, indole quinone. Its chemical name is indol(o)-2,3-dione,it is orange-red monoclinic prism crystal at room temperature. Bitter. The molecular weight is147.13. Melting point 203.5 ℃ (Part sublimation). Dissolved in water, hot ethanol, benzene, acetone, ether-soluble. Soluble in boiling alcohol, soluble in ether and boiling water and it is reddish brown , soluble in caustic and solution is purple, it changes to yellow after placement. Its alcohol solution has a very unpleasant odor. Weakly alkaline, it can salify with a perchlorate. Above information of is edited by Andy from ChemicalBook (2016-11-19). |
| Chemical Properties | Orange-red monoclinic prism crystals. Melting point 203.5 ℃ (Part sublimation). Soluble in hot ethanol, ethyl ether-soluble, soluble in hot water, benzene, acetone, dissolved in alkali metal hydroxide oxide. The solution is purple, it turns yellow after placement, alkaline activity is extremely weak. Bitter. |
| Uses | (1) The product is used as medicine and dye intermediates ,and it is used for the production of drug quinophan, dye disperse Yellow E-3G ; in chemical analysis,it is used as reagents for the determination of copper ions, mercaptans, thiophene, indoxyl-beta-glucoside. (2) Isatin as a reference material for the preparation of indigo and Maya blue; for the preparation of phthalazinone derivatives, spirooxindole derivatives, the expression of P-glycoprotein for multi-drug resistant cells; The ketone is fused to form indole-2-one as a tubercular mycobacterial protein tyrosine phosphatase B, a potent selective inhibitor, as a powerful antimicrobial and antifungal triazole-isatine complex, And the Knoevenagel enrichment reaction; the isatin is activated by the direct sp2/sp3C-H bond, and undergoes a reaction with the cyclopentadienyl-Pd (II) catalyzes the CH addition reaction to form 3-substituted-3-hydroxy 2-oxindole. |
| production method | Condensation of chloral and aniline can generate oximide-acetanilide, and then by cyclization, hydrolysis , isatin is obtained. |
| Chemical Properties | orange-red powder or crystals |
| Uses | manufacture of vat dyes. In analytical chemistry as a reagent for cuprous ions, mercaptans, thiophene, and indican. |
| Uses | Isatin is an endogenous monoamine oxidize (MAO) inhibitor involved in stress and anxiety. Additionally, isatin inhibits alkaline phosphatase (ALP), nitric oxide (NO)-stimulated soluble guanylate cyclase, and other enzymes. Isatins undergo a one-pot Wolff-Kishner like reduction with hydrazine hydrate, under surprisingly mild conditions, to give the corresponding oxindoles. It is used as chromatographic spray reagent for amino acid detection. |
| Uses | Isatin can be used as a reactant to prepare:
It can be a reactant for:
Isatin can also be used as a chromatographic spray reagent for amino acids, and also as a reference material in the preparation of indigo and Maya Blue. It is responsible for the yellow color exhibited by the "Maya Yellow" pigment. |
| Definition | ChEBI: An indoledione that is the 2,3-diketo derivative of indole. |
Product picture
Packing &shipping&Payment
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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- Since: 2017-12-08
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