Product Details
Product Name:
Iroxanadine |
CAS No.:
203805-20-3 |
Purity:
97.92% |
Supply Ability:
10g |
Release date:
2024/11/09 |
Product Introduction
Bioactivity
名稱 | Iroxanadine |
描述 | Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation in guinea pig pulmonary artery preparations precontracted with phenylephrine.CAS ??13480-84-5 |
體內(nèi)活性 | Iroxanadine improves the survival of vascular endothelial cells (ECs) following ischemia/reperfusion stress. ECs cultured from human umbilical veins were exposed to hypoxia/reoxygenation to mimic ischemia/reperfusion. Caspase activation and apoptosis were monitored in the reoxygenated cells. The addition of Iroxanadine (0.1-1 μM) to the culture medium prior to hypoxia or at the start of reoxygenation significantly reduced the caspase-dependent apoptosis.[1] |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 45 mg/mL (172.86 mM)
|
關(guān)鍵字 | Iroxanadine |
相關(guān)產(chǎn)品 | Adezmapimod | Doramapimod | Dihydrocaffeic acid | VX-702 | Bakuchiol | p38α inhibitor 3 | SB 202190 | (-)-Bornyl acetate | MW-150 | Allicin | (E)-Ferulic acid methyl ester | p38-α MAPK-IN-1 |
相關(guān)庫 | 疼痛相關(guān)化合物庫 | 經(jīng)典已知活性庫 | 激酶抑制劑庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
-
CAS:1802220-02-5
$45.00 / 1mg
-
CAS:102771-12-0
$142.00 / 1mg
Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$2580.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 |