IPI-493 NEW
| Price | $293 | $722 | $987 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: IPI-493 | CAS No.: 64202-81-9 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | IPI-493 |
| 描述 | IPI-493 (17-amino17demethoxy) is a novel HSP90 inhibitor with antitumor activity. |
| 體內(nèi)活性 | In Nude mice of GIST-BOE, the oral doses of IPI-493 were 50 mg/kg twice daily, 40 mg/kg once daily, and 100 mg/kg three times weekly. In the GIST-PSW and GIST-48 models, the dose of IPI-493 was reduced to 80 mg/kg with no change in the duration of dosing.IPI-493 treatment resulted in tumor growth stabilization, different degrees of proliferation inhibition, induction of apoptosis and necrosis, and down-regulation of the KIT and its signaling cascade, especially in the GIST-BOE model.IPI-493 treatment significantly reduced vascular density.[5] |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 關(guān)鍵字 | IPI493 | NSC-255109 | 17Amino17demethoxygeldanamycin | IPI-493 | 17Aminogeldanamycin | NSC255109 |
| 相關(guān)產(chǎn)品 | Ethoxyquin | SNX0723 | Tamoxifen | SNX2112 | Teprenone | Elesclomol | Rifabutin | Palmitic acid | Paeoniflorin | Tamoxifen Citrate |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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