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Postion:Product Catalog >Integrin alpha V beta 8 Protein, Human, Recombinant (His)
Integrin alpha V beta 8 Protein, Human, Recombinant (His)
  • Integrin alpha V beta 8 Protein, Human, Recombinant (His)

Integrin alpha V beta 8 Protein, Human, Recombinant (His) NEW

Price $1930
Package 500μg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Integrin alpha V beta 8 Protein, Human, Recombinant (His) Purity: SDS-PAGE: 97.1%; SEC-HPLC: 96.8%
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

NameIntegrin alpha V beta 8 Protein, Human, Recombinant (His)
DescriptionIntegrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cytoskeleton. It binds ligands containing an RGD motif; including vitronectin; fibrin and the latency associated peptide (LAP) of the latent TGF-beta complex. High affinity binding of alpha V beta 8 to LAP allows proteolytic cleavage by MT1-MMP; which releases active TGF-beta. This mechanism differs from that of alpha V beta 6; the other alpha V integrin which can activate TGF-beta from latency through non-proteolytic mechanisms.
StorageShipping with blue ice.

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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