IMMH 010 maleate NEW
| Price | $195 | $483 | $692 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: IMMH 010 maleate | CAS No.: 2541982-47-0 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | IMMH 010 maleate |
| Description | IMMH 010 maleate (YPD-30 maleate) is an orally available programmed cell death ligand 1 inhibitor with potential antitumor activity for the study of neurological disorders and advanced malignant solid tumors. |
| In vitro | IMMH-010 maleate (YPD-30) is an ester prodrug of YPD-29B, which is an effective small-molecule inhibitor targeting hPD-L1 in vitro[1]. |
| In vivo | IMMH-010 maleate (YPD-30; 2.5, 5, and 10 mg/kg; oral administration, twice weekly) significantly delayed tumor progression in mice compared to the vehicle group in a dose-dependent manner. The tumor growth inhibition rates (TGI) were 40.5% (2.5 mg/kg), 60.9% (5 mg/kg), and 67.9% (10 mg/kg), respectively[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Keywords | IMMH010maleate |
| Inhibitors Related | LSD1-IN-24 | PD-1/PD-L1-IN-9 | Sulfamethoxypyridazine | PD-1-IN-22 | BMS-202 | BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride | LSD1-IN-27 | PD-1/PD-L1-IN-10 | BMS-1 | PD-L1-IN-3 |
| Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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