IFN alpha-IFNAR-IN-1 hydrochloride NEW
Price | $41 | $59 | $96 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-12 |
Product Details
Product Name: IFN alpha-IFNAR-IN-1 hydrochloride | CAS No.: 2070014-98-9 |
Purity: 99.66% | Supply Ability: 10g |
Release date: 2024/11/12 |
Product Introduction
Bioactivity
名稱 | IFN alpha-IFNAR-IN-1 hydrochloride |
描述 | IFN alpha-IFNAR-IN-1 hydrochloride is an inhibitor of the interaction between IFN-α and IFNAR, effectively inhibiting MVA-induced IFN-α responses by BM-pDCs with an IC50 of 2-8 μM. |
體外活性 | IFN alpha-IFNAR-IN-1 hydrochloride inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 hydrochloride specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 hydrochloride exerts immunosuppressive activity by the direct interaction with IFN-α[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | H2O : 16 mg/mL (50.66 mM), Sonication is recommended. DMSO : 95 mg/mL (300.77 mM), Sonication is recommended. |
關(guān)鍵字 | IFN alpha-IFNAR-IN-1 Hydrochloride | IFN α-IFNAR-IN-1 Hydrochloride | Inhibitor | Interferon-α/β receptor | Interferon-alpha/beta receptor | IFN a-IFNAR-IN-1 Hydrochloride | inhibit | IFN alpha IFNAR IN 1 hydrochloride | IFNAR | IFN alphaIFNARIN1 hydrochloride |
相關(guān)產(chǎn)品 | Deucravacitinib | Ginsenoside F3 | Anti-Mouse IFN gamma Antibody (H22) | RO8191 | Tilorone dihydrochloride | Anifrolumab | AX-024 hydrochloride | Interferon receptor inducer-1 | Vadimezan | Monalizumab | Cridanimod | CCCP |
相關(guān)庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | PPI抑制劑庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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