Product Details
| Product Name:
IDO1-IN-21 |
CAS No.:
2892432-98-1 |
| Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | IDO1-IN-21 |
| Description | IDO1-IN-21 (compound 10m), with an IC50 of 0.64 μM, acts as an IDO1 inhibitor and has demonstrated efficacy in suppressing tumor growth in murine models [1]. |
| In vitro | IDO1-IN-21, administered at concentrations ranging from 0 to 50 μM for 48 hours, inhibits the viability of SW480 cells, with an IC50 value of 28.64 μM [1]. At a lower concentration range of 0 to 10 μM over 48 hours, IDO1-IN-21 suppresses IDO1 activity in HeLa cells, with an IC50 value of 1.04 μM [1]. |
| In vivo | IDO1-IN-21 (50, 100 mg/kg; i.p.; every three days for 21 consecutive days) inhibited tumor growth in CT26 tumor-bearing mice [1]. |
| Storage | Shipping with blue ice. |
| Inhibitors Related | Palmatine chloride | GNF-PF-3777 | Coptisine chloride | Necrostatin-1 | IDO-IN-7 | Coptisine sulfate | Indoximod | Palmatine | IDO inhibitor 1 | Epacadostat | IDO5L | IDO-IN-12 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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