Icariin can increase cardiovascular and cerebrovascular blood flow, promote hematopoietic function, immune function and bone metabolism, and has the effects of tonifying kidney and strengthening Yang, anti-aging and anti-tumor. 1. Effect on endocrine: Icariin can promote sexual function due to hypersecretion of semen, full of seminal vesicles, stimulation of sensory nerves, and indirect excitement of sexual desire. 2. Impact on immune system function: The number of T cells, turnover rate, antibody, antigen and phagocytosis function of reticuloendothelial system in patients with kidney deficiency are low, which can be improved by the treatment of kidney tonifying drugs such as Epimedium. 3, anti-aging effect: Icariin can affect the aging mechanism from different aspects. For example, it affects cell passage, prolongs growth period, regulates immune and secretory systems, improves body metabolism and organ functions. 4. Effect on cardiovascular system: Icariin on posterior pituitary

Pharmacological action

1. Effect on sexual function The extract of Epimedium has a certain role in promoting gonadal function. Flavonoids such as icariin have the function of tonifying kidney and aphrodisiac. 30 ~ 1000μg/l can promote the secretion of estradiol by follicular granulocytes, and 1000μg/l can promote the secretion of corticosterone by adrenal cortical cells. At the same time, EPS can increase the level of gonadal hormone, mainly increase the level of FSH.

2. Improving the immune function of pubertal epimedium by 50% methanol extract can inhibit lymphocyte transformation. The total flavone of Epimedium can make the "Yang deficiency" mice form higher cell function and antibody, and obviously enhance the human T cell immune function. Both EPS and EI have immunomodulatory effects.

3. Antioxidant EPS and EI both have antioxidant activities, which can enhance the activity of antioxidant enzymes and reduce the effect of free radical products.

4. Anti-aging effect Epimedium extract can resist aging and prolong life by affecting cell passage, prolonging growth period, regulating immune and secretory systems, improving body metabolism and organ functions.

5. The non-amino acids in the extract of epimedium alcohol can significantly increase the coronary artery flow of isolated rabbit hearts. Decoctions and alcohols can lower blood pressure. Icariin can directly relax vascular smooth muscle and dilate coronary artery, femoral artery and cerebral artery. The mechanism of action is to inhibit the intracellular calcium ion flow in vascular smooth muscle.