I3MT-3 NEW
Price | $70 | $172 | $272 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: I3MT-3 | CAS No.: 459420-09-8 |
Purity: 99.86% | Supply Ability: 10g |
Release date: 2024/11/18 |
Product Introduction
Bioactivity
名稱 | I3MT-3 |
描述 | I3MT-3 (HMPSNE) (HMPSNE) is a potent, selective and cell membrane permeability inhibitor of 3-mercaptopyruvate sulfur transferase (3MST), which targets the persulfated cysteine residues located at the active site of 3MST. |
體外活性 | I3MT-3 shows a dose-dependent inhibition of 3-MST activity from CT26 homogenates, which contain the murine form of the enzyme. The IC50 of HMPSNE for murine 3-MST is calculated as 2.3 μM with a cozncentration-dependent decrease of AzMC fluorescence[1].I3MT-3 (0-300 μM; 48 hours) inhibits CT26 cells proliferate with increasing concentrations of I3MT-3. Confluence of cells treated with HMPSNE is recorded each hour for 48 h by the IncuCyte method[2]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 120 mg/mL (386.64 mM) |
關(guān)鍵字 | EA.hy926 cells | Hippo (MST) | inhibit | 3MST | I3MT-3 | HEK293 | I3MT3 | cell-membrane | COS-7 | I-3MT-3 | I3MT 3 | Inhibitor |
相關(guān)產(chǎn)品 | XMU-MP-1 | Pim1/AKK1-IN-1 | IHMT-MST1-58 | Cerdulatinib hydrochloride |
相關(guān)庫 | 經(jīng)典已知活性庫 | 激酶抑制劑庫 | 抑制劑庫 | NO PAINS 化合物庫 | 抗前列腺癌化合物庫 | 干細胞分化化合物庫 | 已知活性化合物庫 | 共價抑制劑庫 | 抗癌化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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