Hypromellose NEW
| Price | $39 |
| Package | 10g |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Hypromellose | CAS No.: 9004-65-3 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Hypromellose |
| Description | Hypromellose (HPMC) is a water-soluble hydrophilic, non-ionic cellulose ether. |
| In vitro | Hypromellose (hydroxypropylmethylcellulose) is a long-established component of sustained-release pharmaceutical formulations. In matrix tablets, this polymer rapidly absorbs water, forming a viscous gel barrier that encapsulates the tablet. The modulation of drug release rates by hypromellose is governed by several factors, including the water diffusion rate into the polymer, the kinetics of hypromellose hydration and subsequent gelation, the viscosity of the gel produced, and the erosion rate of the gel layer [2]. This mechanism enables hypromellose to facilitate a controlled drug release, extending the drug's therapeutic efficacy [1]. |
| In vivo | Punctal occlusion using hypromellose 2% is a low-cost and safe additional treatment for dry eye, significantly reducing symptoms as indicated by fluorescein and rose bengal staining tests [3]. Hypromellose also improves blood glucose metabolism and suppresses oxidative stress in mice on a high-fat diet, likely through the regulation of hepatic glucose-regulating enzyme activities and activation of hepatic and erythrocyte antioxidant enzymes [4]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 12.61 mg/mL (10 mM), Sonication is recommended. H2O : 9 mg/mL, Sonication is recommended. |
| Keywords | Celacol HPM5000 | inhibit | Hypromellose | Inhibitor | Celacol HPM-5000 |
| Related Compound Libraries | Food Additive Library | Cosmetic Ingredient Compound Library | Inactive Ingredient Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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