HPK1-IN-35 NEW
Price | $1520 | $1980 | $2500 |
Package | 25mg | 50mg | 100mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: HPK1-IN-35 | CAS No.: 2935903-77-6 |
Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | HPK1-IN-35 |
Description | HPK1-IN-35 is a potent, selective inhibitor of HPK1, demonstrating an IC50 value of 3.5 nM. This compound reduces p-SLP76 expression and facilitates the secretion of IL-2 [1]. |
In vitro | HPK1-IN-35 (compound 31) reduces anti-CD3 antibody (1 μg/mL)-stimulated p-SLP76 expression dose-dependently at concentrations of 0.1, 0.3, 1, and 3 μM after 1 hour of treatment [1]. Furthermore, HPK1-IN-35 enhances IL-2 secretion from Jurkat cells in a dose-dependent manner within the range of 0-10 μM over 24 hours, with an EC50 value of 1.19 μM [1]. |
Storage | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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- Since: 2011-01-07
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