HIV-1 integrase inhibitor 8 NEW
Price | $40 | $92 |
Package | 100mg | 500mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: HIV-1 integrase inhibitor 8 | CAS No.: 1568-80-5 |
Purity: 98.01% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | HIV-1 integrase inhibitor 8 |
Description | HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase, a critical enzyme necessary for the integration step in HIV replication [1]. |
In vitro | HIV-1 integrase inhibitor 8 were tested against 3′-processing (TC) and strand-transfer (ST) activities in the presence of Mn2+ as the cationic cofactor by gel assay, IC50=275μM and 231μM, respectively. HIV-1 integrase inhibitor 8 were retested using Mg2+ and the IC50 of against strand-transfer (ST) activities was 200μM. HIV-1 integrase inhibitor 8 inhibits MCV topoisomerase and DNA religation with IC50 of 500 μM and 200 μM, respectively. HIV-1 integrase inhibitor 8 induces cell cytotoxicity with LD50 of 20 μM in HeLa cells[1]. |
Storage | Shipping with blue ice. |
Solubility Information | DMSO : 45 mg/mL (145.91 mM), Sonication is recommended. |
Inhibitors Related | Stavudine | Emtricitabine | Lamivudine |
Related Compound Libraries | Bioactive Compound Library | Anti-Viral Compound Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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