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Postion:Product Catalog >HG-10-102-01
HG-10-102-01
  • HG-10-102-01

HG-10-102-01 NEW

Price $53 $86 $173
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: HG-10-102-01 CAS No.: 1351758-81-0
Purity: 99.59% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameHG-10-102-01
DescriptionHG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).
In vivoHG-10-102-01 substantially inhibits Ser910 and Ser935 phosphorylation of both wild-type and G2019S mutant LRRK2 in cells.?When given intraperitoneally, HG-10-102-01 penetrates the blood-brain barrier and inhibits phosphorylation of LRRK2 in the brain as well as the kidney and spleen.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (132.33 mM)
KeywordsParkinson’s disease | Leucine-rich repeat kinase 2 | inhibit | HG-10-102-01 | Ser910 | BBB | HG 10 102 01 | Radiosynthesis | Mouse embryonic fibroblast cells | Mouse Swiss 3T3 cells | MAP kinase interacting kinase | Ser935 | MNK | Mitogen activated protein kinase interacting kinase | HG1010201 | PET | Inhibitor | MAPK interacting kinase | HEK293 cells | LRRK2 | Positron emission tomography
Inhibitors RelatedPFE-360 | GNE0877 | CZC-25146 | GSK2578215A | GNE-9605 | CZC-54252 hydrochloride | GNE-7915 | EB-42486 | LRRK2 inhibitor 1 | LRRK2-IN-7 | LRRK2-IN-1 | CCG-1423
Related Compound LibrariesAnti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Parkinson's Disease Compound Library | Autophagy Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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