HDAC-IN-51 NEW
| Price | $195 | $430 | $636 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: HDAC-IN-51 | Purity: 97.19% |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | HDAC-IN-51 |
| Description | HDAC-IN-51 is an HDAC inhibitor. |
| In vitro | HDAC-IN-51 (compound 8d) (1 nM-10 μM; 48 h) has antiproliferative activity with IC50 values of 0.54, 0.56, and 1.35 μM against K562, HCT116, and A549 cells, respectively.[1] HDAC-IN-51 (1, 5 μM; 24, 48 h; U937 leukemia cells) arrests the cell cycle in the G1 phase.[1] HDAC-IN-51 (1, 5 μM; 48 h; U937 cells) induces apoptosis and downregulates miRNAs with anti-apoptotic activity (miR-17-5p, miR-18-5p, miR-19b-3p, miR-20a-5p and miR-21-5p).[1] HDAC-IN-51 (1, 5 μM; 48 h; U937 cells) increases the mRNA expression of p21, BAX, and BAK and downregulates cyclin D1 and BCL-2.[1] |
| Storage | Shipping with blue ice. |
| Solubility Information | DMSO : 45 mg/mL (103.09 mM) |
| Inhibitors Related | Valproic acid sodium salt | Panobinostat | Theophylline monohydrate | Sodium 4-phenylbutyrate | Vorinostat | Acefylline | Curcumin | Valproic Acid | Parthenolide | 4-Phenylbutyric acid | Theophylline | Methyl L-histidinate dihydrochloride |
| Related Compound Libraries | Histone Modification Compound Library | Bioactive Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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