Description of HATU from Watson Biotechnology Co., Ltd

Specifications(COA) of HATU CAS 148893-10-1 Coupling Reagent Peptide Synthesis

HATU (1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a coupling reagent commonly used in organic chemistry, particularly in peptide synthesis. Its primary applications include:

1. Peptide Bond Formation: HATU is widely used in solid-phase peptide synthesis (SPPS) and solution-phase peptide synthesis. It facilitates the formation of peptide bonds by activating carboxyl groups of amino acids to react with amines, forming amide bonds efficiently.

2. Amide Bond Formation: Beyond peptide synthesis, HATU is used for forming amide bonds in various organic reactions. It is particularly useful for coupling carboxylic acids with amines to form amides.

3. Increased Efficiency and Yield: HATU provides higher coupling efficiency and yields compared to other coupling reagents like HBTU and DCC. It minimizes racemization, which is critical in synthesizing peptides with chiral centers.

4. Compatibility with Mild Conditions: HATU works under relatively mild reaction conditions, making it suitable for sensitive substrates that might degrade under harsher conditions.

5. Broad Substrate Scope: It is effective with a wide range of substrates, including sterically hindered and electronically diverse amino acids and carboxylic acids.

Overall, HATU is valued for its efficiency, reliability, and broad applicability in synthesizing peptides and other amide-containing compounds.

Founded in 2006 and headquartered in Wuhan, Hubei, China, Watson Biotechnology Co., Ltd is a leading manufacturing powerhouse specializing in the production of Active Pharmaceutical Ingredients (APIs) and Intermediates, Food and Feed Additives, Agricultural and Aquaculture chemicals, and Fine Chemicals. As a dedicated factory, our operations are driven by a commitment to excellence and innovation, ensuring that our products meet the highest standards of quality and compliance.

With a robust team of over 100 skilled professionals, Watson Biotechnology has established itself as a trusted name in the industry. Our products are meticulously crafted to align with international standards such as USP (United States Pharmacopeia), EP (European Pharmacopoeia), and BP (British Pharmacopoeia), guaranteeing reliability and efficacy.

At Watson Biotechnology, we pride ourselves on our cutting-edge facilities and state-of-the-art technology, which enable us to deliver superior products that cater to a diverse range of needs across various sectors. Our dedication to continuous improvement and customer satisfaction drives us to maintain stringent quality control processes and foster an environment of innovation and growth.

Watson Biotechnology Co., Ltd is a professional manufacturer which provide HATU with good quality and best price, welcome to contact us to get COA/TDS/MSDS of HATU.